demsoplastic small round cell tumor:a diagnostic and therapeutic dilemma
Authors
abstract
desmoplastic small round cell tumor (dscrt) is a rare variant of sarcoma with a highly aggressive behavior. it usually affects abdominal cavity and has a male predominance. its correct diagnosis and treatment is sophisticated and requires an experienced multidisciplinary team. hereby we present a 25 yrold man from kerman province in 2013 with abdominal mass and ascites who underwent sonograghy guided percutaneous needle biopsy which was misleading and inconclusive for diagnosis. thus an open biopsy was fulfilled which revealed solid nests of small round cells with hyperchromatic nuclei and clear cytoplasm surrounded by a desmoplastic stroma suggestive for dscrt. the diagnosis was confirmed by positive immunohitochemical reaction for cytokeratin, desmin and neuron specific enolase(nse).ultimately the patient underwent chemotherapy on the basis of p6 protocol without surgical debulking.diagnosis and treatment of dscrt could be a dilemma due to its rarity, various clinicopathologic mimickers and lack of a consensus about its management.
similar resources
Demsoplastic Small Round Cell Tumor:a Diagnostic and Therapeutic Dilemma
Desmoplastic small round cell tumor (DSCRT) is a rare variant of sarcoma with a highly aggressive behavior. It usually affects abdominal cavity and has a male predominance. Its correct diagnosis and treatment is sophisticated and requires an experienced multidisciplinary team. Hereby we present a 25 yrold man from Kerman Province in 2013 with abdominal mass and ascites who underwent sonograghy ...
full textDemsoplastic Small Round Cell Tumor: a Diagnostic and Therapeutic Dilemma.
Desmoplastic small round cell tumor (DSCRT) is a rare variant of sarcoma with a highly aggressive behavior. It usually affects abdominal cavity and has a male predominance. Its correct diagnosis and treatment is sophisticated and requires an experienced multidisciplinary team. Hereby we present a 25 yr old man from Kerman Province in 2013 with abdominal mass and ascites who underwent sonography...
full textHighly cellular leiomyoma mimics a malignant small round-cell tumor: a diagnostic dilemma on frozen sections.
OBJECTIVE Cellular leiomyoma is characterized by significantly increased cellularity and may mimic malignant tumors. Our aim was to differentiate these from other malignant small round-cell tumors. CASE REPORT We report a case of cellular leiomyoma that mimicked a malignant small round-cell tumor upon frozen section examination. CONCLUSION Pathologists should be aware that highly cellular l...
full textClear cell odontogenic carcinoma: a diagnostic and therapeutic dilemma
BACKGROUND Clear cell odontogenic carcinoma is a rare odontogenic tumor occurring in the anterior region of the mandible in 5th-7th decades and shows a female preponderance. It is potentially aggressive, capable of frequent recurrences and loco-regional and distant metastases. CASE PRESENTATION A 45-year-old woman presented with a radiolucent left mandibular swelling associated with loss of t...
full textMyeloid Sarcoma Presenting with Lateral Cervical Mass and Eosinophilia; a Diagnostic and Therapeutic Dilemma: Case Report
Myeloid sarcoma is a rare extramedullary tumor of immature myeloid cells. It has been very rarely reported as lateral cervical mass in English literature. Myeloid sarcoma has also been reported with marked eosinophilia. Here we present a 17 year old boy with lateral cervical mass and persistent eosinophilia. The mass was isointense in MRI and homogenously enhanced after contrast injection which...
full textMy Resources
Save resource for easier access later
Journal title:
iranian journal of pathologyجلد ۱۱، شماره ۳، صفحات ۲۵۵-۲۶۰
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023